Atherosclerosis

Atherosclerosis - is an inflammatory-fibroproliferative process that results from the collection of plasma- origin atherogenic lipoproteins in the artery intimacy. Atherosclerosis atheroma or atheromatous or fibrosis fatty plaque are characterized by intimal damage which can surge toward the vascular culvert and narrow the culvert, weaken tunica media and cause severe complications. Mainly, cholesterol accumulation in the vein walls causes the most common pathology – the formation of atherosclerosis. There are special lipid plaques around the connective tissues. As a result, vascular damage occurs. The veins lose their elasticity, become solid, and the blood supply is violated in the tissues. There is a thrombus in the plaque. As a result of hyperlipoproteins, atherosclerosis develops. All the lipoproteines except chilomicrons enter into the walls of the vessels. However, α-lipoproteins, which are rich in protein and phospholipids, are disintegrated on the vessel walls or are not accumulated there as they are small in size. All of the β-lipoproteins, a part of pre-β-lipoproteides, are richer with cholesterol. Increase in the amount of this class of lipoproteins in the blood increases the permeability of the walls of the vessels and there is the collection of atherogenic lipoproteins. As a result, it causes the formation of atherosclerosis.